Vine Resveratrol + Hyaluronic Acids
Reverse skin aging
Patent pending: PCT/IB2015/054257 filed by Caudalie and Harvard University
Caudalie has filed a patent and been granted an exclusive license to a new technology developed jointly by Caudalie scientists and Dr. David Sinclair of Harvard Medical School.
Research in the Sinclair lab at Harvard Medical School had unveiled a surprising synergy between a molecule called Resveratrol, produced in the stalk of grapevines and other fruits, and a complex of micro-hyaluronic acid. The combination, they found, leads to an overproduction in cells of natural hyaluronic acid.
Hyaluronic acid is naturally present in the skin and plays an important role in hydration and in preserving the biomechanical properties of the skin. A decrease in hyaluronic acid quantity and quality with age causes a decline in these properties, leading to dryness and the appearance of wrinkles.
An unprecedented collaboration
The technology is protected by a patent application filed jointly between Caudalie and Harvard University’s Office of Technology Development (OTD). Harvard OTD granted Caudalie an exclusive right to practice the patent in the fields of cosmetics, nutritional supplements, and injectable aesthetics.
Caudalie is an authority and pioneer of stabilized resveratrol in skincare and patented the first version in 1997, making it lipophilic to penetrate the skin. The company’s collaboration with the Sinclair Lab at HMS, focused on understanding the effects of resveratrol on cellular mechanisms related to aging, began in 2013.
"I was excited to see how well the two ingredients worked together (…) One of the challenges associated with products containing hyaluronic acid has been that the molecule is large and therefore poorly absorbed. Stimulating the Has2 gene is a very interesting approach because it prompts the cells to make their own molecules from within."
- Dr. David Sinclair, Harvard Medical School -